Managed Care


Diagnostics in Oncology: A New Paradigm for Tumor Profiling and Treatment Options

Diagnostics in Oncology: A New Paradigm for Tumor Profiling and Treatment Options

In 2007, the American Cancer Society estimated that approximately 178,460 new cases of breast cancer would be diagnosed and 40,460 women would die from the disease. Nearly half of the new cases were expected to be categorized as node-negative, estrogen-receptor (ER)-positive. Although the benefit of ER blockade in combination with chemotherapy has been demonstrated in women with node-negative, ER-positive tumors, low distant recurrence rates with ER blocker monotherapy suggest that chemotherapy may provide minimal benefit in most cases. Molecular diagnostics represent a paradigm shift in breast cancer management, allowing treatment decisions to be based on the genetic profile, or signature, of an individual tumor. Alan H. Heaton, PharmD, RPh; David Hyams, MD; Jill M. Kolesar, PharmD, BCPS, FCCP; and Winston Wong, PharmD discuss the innovative gene expression profiling tools that can help to determine the aggressiveness and prognosis of the cancer, and to predict the likely benefit from a specific treatment.

This supplement is based on a satellite symposium held at the Academy of Managed Care Pharmacy 20th Annual Meeting & Showcase in San Francisco on April 17, 2008.

  • Understanding Tumor Profiling and Assessing Treatment
  • Assessing Therapeutically Developed Assays
  • Health Plan Integration of Molecular Diagnostics
  • Roundtable Discussion: Using Molecular Diagnostics in Managed Care


2014 Annual HEDIS® and Star Ratings Symposium Nashville, TN November 3–4, 2014
PCMH & Shared Savings ACO Leadership Summit Nashville, TN November 3–4, 2014
Medicare Risk Adjustment, Revenue Management, & Star Ratings Fort Lauderdale, FL November 12–14, 2014
World Orphan Drug Congress Europe 2014 Brussels, Belgium November 12–14, 2014
Healthcare Chief Medical Officer Forum Alexandria, VA November 13–14, 2014
Home Care Leadership Summit Atlanta, GA November 17–18, 2014
6th Semi-Annual Diagnostic Coverage and Reimbursement Conference Boston December 4–5, 2014
Customer Analytics & Engagement in Health Insurance Chicago December 4–5, 2014
Pharmaceutical and Biotech Clinical Quality Assurance Conference Alexandria, VA December 4–5, 2014
9th Semi-Annual Medical Device Coverage and Reimbursement Conference San Diego December 5, 2014
8th Annual Medical Device Clinical Trials Conference Chicago December 8–9, 2014
HealthIMPACT Southeast Tampa, FL January 23, 2015