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February 2010

Features

Cover Story

Meaningful Use: Tasty Carrot or Big, Brutal Stick?
The stimulus bill’s $27 billion for health information technology will go to providers, but health plans will experience other financial and operational benefits.

HIT Decisions Lie on the Horizon, But Savings Remain Elusive
How electronic health records, in their many manifestations, will transform health care should be evident within a couple of years. Will the potential be realized?

Generics Offer Pharmacy Plans Specific Benefits
Administrators find themselves with pricing leverage they’ve never had before

Health Management Uses IT To Reduce Future Costs
Payers must manage the care of all members, regardless of how sick or well, to control escalating treatment expenditures

Q&A

A Conversation with AHRQ’s P. Jon White, MD
AHRQ’s director of health care information technology looks at the federal health care IT stimulus program from the quality perspective

Peer-Reviewed

Impact of 17P Usage on NICU Admissions In a Managed Medicaid Population — A Five-Year Review

Departments

Editor’s Memo
A Lot Is Riding On ‘Meaningful Use’

Snapshot
Membership falls at most of the biggest plans

Medication Management
Health Plans Walk a Clinical Tightrope When Treating Adolescents for Depression
Notwithstanding a black box warning from the FDA, ongoing research demonstrates the efficacy of treating adolescents and children with antidepressants

Compensation Monitor
Medical groups can receive 2% bonus from CMS

Plan Watch
500 Patients in San Diego Might Revolutionize Care
Kaiser Permanente and the federal government believe that they’ve found the path to a national health record system

Tomorrow’s Medicine
Mitral Valve Clip’s Value? Fewer Open Chest Surgeries
Inspired by an anatomic variant in a patient, a double-orifice control device alleviates mitral regurgitation

Managed Care Outlook
Medical school costs deter qualified candidates

News

What a bargain: Employer-sponsored health plans
Headlines on Deadline
Stroke Survivors Often Forsake Preventive Drugs
Plans Help Bridge Cost Discussion
CMS Fields Provider Survey

Review of the Clinical Information for SIMPONI™ (golimumab) In Rheumatoid Arthritis

This Clinical Brief reviews the clinical information for SIMPONI™ (golimumab), which was approved by the U.S. Food and Drug Administration on April 24, 2009, for the treatment of adults with moderately to severe active rheumatoid arthritis (RA) in combination with methotrexate (MTX). It is also indicated for treatment of adults with active psoriatic arthritis, alone or in combination with MTX, and adults with active ankylosing spondylitis.

Highlights:

  • SIMPONI™ is administered in a one dose, once a month subcutaneously via a prefilled autoinjector or prefilled syringe.
  • SIMPONI™ has been studied in three phase 3 trials that enrolled different patients populations with respect to treatment. These multicenter, randomized, double-blinded, placebo-controlled trials included 1,542 patients age 18 or older with moderately to severely active RA.
  • In these three trials, SIMPONI™ was shown to improve the signs and symptoms in patients with moderately to severely active RA. It also was shown to be efficacious in patients who are incomplete responders or naïve to MTX, as well as those patients who have been previously treated with at least one other anti-tumor necrosis factor agent.

Roy Fleischmann, MD, Clinical Professor of Medicine, University of Texas Southwestern Medical Center, and Co-Medical Director, Metroplex Clinical Research Center, Dallas, discusses this novel agent.

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