Peer-Reviewed Articles from Managed Care


Meeting the Challenges and Burdens Associated With Hereditary Angioedema

With the advent of new disease-specific agents, some patients with HAE may find relief from its enormous physical and psychological toll

Michael Toscani, PharmD; Marc Riedl, MD, MS


Outcomes and Costs Associated With Initial Maintenance Therapy With Fluticasone Propionate-Salmeterol Xinafoate 250 μg/50 μg Combination Versus Tiotropium In Commercially Insured Patients With COPD

The comparison found that maintenance therapy with fluticasone propionate-salmeterol combination was associated with a 14% reduction in risk of severe exacerbation, less health care utilization, and 25% lower COPD-related medical costs

Anand A. Dalal, PhD; Sean D. Candrilli, PhD; Keith L. Davis, MA


Health Care Costs Associated With Treatment Modification in Type 2 Diabetes Mellitus Patients Taking Oral Anti-diabetic Drugs

A comparison of health care costs in patients with diabetes who do not initially respond to oral therapy suggests that it might be appropriate and clinically beneficial for providers to consider adding another oral agent, rather than up-titrating the current medication, particularly beyond intermediate dose levels

Girishanthy Krishnarajah, MPH, MBA/MS; Monali Bhosle, PhD; Richard Chapman, PhD


Economic Benefits of Improved Insulin Stability In Insulin Pumps

Richard C. Weiss, BS, MS; Derek van Amerongen MD, MS; Gary Bazalo, BS, MS, MBA; Mark Aagren, MS; Jonathan R. Bouchard, MS, RPh


Effects of a Pregnancy Management Program On Birth Outcomes in Managed Medicaid

Low-birth-weight outcome was reduced when women participated in a managed maternity program, compared with nonparticipants

Mary V. Mason MD, MBA, FACP; Amy Poole-Yaeger MD, FAAP; Brad Lucas MD, MBA, FACOG; Cathie R. Krueger, RN, BSN; Tamim Ahmed, Ph.D, MBA; Ian Duncan, FSA, FIA, FCIA, MAAA


Health Care Utilization & Costs For Cystic Fibrosis Patients with Pulmonary Infections

Amy K. O'Sullivan, PhD; Jane Sullivan, MPH; Keiko Higuchi, MPH; A. Bruce Montgomery, MD


How the Doughnut Hole Affects Prescription Fulfillment Decisions Involving Cardiovascular Medications For Medicare Part D Enrollees

As Part D enrollees approach their coverage limits, their decisions are significantly affected through the doughnut hole period

John W. Hales, MA, PhD; Stephen George, PharmD, MS, RPh


Identifying Characteristics of Patients With Low Urgency Emergency Department Visits In a Managed Care Setting

A straightforward method of identifying potentially non-urgent ED visits from administrative data can be employed to calculate population-based rates, which might be applied in the development of managed care programs

James W. Davis, PhD; Ronald Y. Fujimoto, DO; Henry Chan, BS; Deborah T. Juarez, Sc.D


Cost-Sharing Effects on Adherence and Persistence For Second-Generation Antipsychotics In Commercially Insured Patients

Teresa B. Gibson, PhD; Yonghua Jing, PhD; Edward Kim, MD, MBA; Erin Bagalman, MSW; Sara Wang, PhD


Comparison of Amlodipine/Valsartan Fixed-Dose Combination Therapy and Conventional Therapy

The use of a single-pill combination of amlodipine/valsartan resulted in higher acquisition costs but fewer clinic visits, laboratory tests, and electrocardiograms — and therefore lower gross costs — compared with the use of individual drug components

Mark A. Malesker, PharmD; Daniel E. Hilleman, PharmD

more