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MANAGED CARE May 2007. ©MediMedia USA

The Appropriate Omalizumab Patient

Management of the uncontrolled asthma patient and case examples

Jill Karpel, MD, Donald A. Bukstein, MD,* Robert LoNigro, MD†

Beth Thalheim Asthma Center, North Shore University Hospital, Manhasset, N.Y.; *Family Medicine at University of Wisconsin–Madison; †Tufts Health Plan, Boston, Mass.

Abstract

Allergy is a significant component in many asthma patients. Omalizumab is a monoclonal anti–immunoglobulin E antibody for the treatment of allergic asthma. Clinical trials have shown that omalizumab treatment is associated with improved symptom control and reduced inhaled corticosteroid doses, resulting in fewer exacerbations and reduced utilization of resources. Omalizumab therapy may benefit patients who remain uncontrolled or who cannot tolerate standard therapy.

Key words: adult, asthma, immunoglobulin E, monoclonal antibody, prior authorization

Corresponding author:

Jill Karpel, MD
Mailing Address:
410 Lakeville Road, Suite 107
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